Highlights:
- AEROPATH (www.aeropath.eu ) is an ambitious multidisciplinary research programme designed to support early stage antimicrobial drug development.
- The project aims to advance understanding, at the molecular level, of fundamental and important aspects of the biology of Gram-negative bacteria targeting in particular the important pathogen Pseudomonas aeruginosa. Modern technologies in chemo-bioinformatics, proteomics, molecular and structural biology, computational chemistry and screening technologies will be exploited to identify ligands and inhibitors (hit and lead compounds) with the potential to drive the discovery of improved therapies for Gram-negative infections.
- We are currently looking for a highly motivated computational chemist to be part of a multi-disciplinary team to apply molecular modeling methods towards the discovery and optimization of inhibitors of key enzymes of gram-Negative pathogens.
- The post is available immediately until 31/10/2012. The level of appointment is flexible and will depend on experience and track record. Training, as required will be provided in a supportive environment enabling researchers to extend their skills and expertise. Career progression is important and staff will be encouraged to participate in a wide range of research, and in this the ability to work well in a team will be critical. The successful candidate will benefit from access to cutting edge facilities in computationally chemistry, crystallography, biochemistry, synthetic and medicinal chemistry, and drug discovery.
